New Diagnostic Tool Throws Light on Rare Eye Disease


Blurred imaginative and prescient, floaters, and strange mild notion – these affected by the uncommon illness posterior uveitis really feel no ache. However the penalties will be extreme: About 5 to 10 p.c of blindness worldwide is attributable to uveitis.

There are totally different types of the illness. In posterior uveitis, the retina or choroid within the eye turns into infected. Whereas the retina converts the incident mild into nerve impulses, the choroid provides the outer layers of the retina with vitamins.


Nonetheless, for the reason that totally different subtypes usually require a unique therapeutic method, a dependable analysis is all of the extra essential. That is why researchers from the Ophthalmology Division on the College of Bonn investigated a brand new imaging method that may help within the analysis of posterior uveitis.

The group evaluated color-coded fundus autofluorescence (Spectrally Resolved Autofluorescence Imaging). The CenterVue (iCare) firm from Padua (Italy) offered the newly developed system to the researchers for the examinations.

Autofluorescence: An Rising Eye Illness Software

This course of entails illuminating the retina with bluish mild. The retina absorbs the sunshine and emits it once more at a unique wavelength. The system measures this fluorescence and splits the indicators right into a inexperienced and a purple part.

The green-to-red ratio of the sunshine emitted from every inflammatory focus relies upon, amongst different components, on the precise posterior uveitis subtype concerned. The researchers examined the eyes of 45 research individuals.

In all of them, the precise subtype of uveitis was identified beforehand. This included ophthalmologic examination findings, laboratory investigations, serologic and radiologic findings, and in some instances genetic and interdisciplinary medical examinations.

The researchers evaluated the green-red ratio within the fluorescence of the fundus of the attention for about 800 inflammatory foci within the eyes of the sufferers. The intention is to doc illness development on a long-term foundation and to develop suggestions for therapy tips.

This know-how may permit higher monitoring of posterior uveitis sooner or later, along with extra dependable diagnoses.

Supply: Eurekalert


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